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KMID : 0359919940130030638
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Korean Journal of Nephrology
1994 Volume.13 No. 3 p.638 ~ p.642
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A Case of Abdominal Neurilemmoma with Erythrocytosis in Hemodialysis Patient
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Abstract
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Erythropoietin (EPO0 is a glycoprotein hormon that control red blood cell production by stimulating the proliferation and differentiation of erythroid progenitor cells. Several tumors, such as renal cell carcinoma, polycystic kidney,
nephroblastoma
and
other few kind of tumors are known to produce EPO and manifest erythrocytosis as a paraneoplastic syndrome. But there is no reported cases about EPO producing neurilemmoma around the world.
We have expierienced a 34 year-old hemodialysis patient with increased hemoglobin and elevated serum EPO level. The patient had typical uremic anemia at the time of initial diagnosis of chronic renal failure. But hemoglobin became to increase,
with
growing of intraabdominal tumor, to 15.2gm/dl at the time of tumor resection. Serum EPO level measured by RIA was 224mUI/dl. The tumor was confirmed as a neurilemmoma in histopathologic examination. Serum EPO level and hemoglobin decreased to
72mIU/ml
and 7.4gm/dl two months after tumor resection. Now, the patient is followed up with the supportive treatment for anemia
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